From an article on Digikey.com
As an alternative to commonly used passive cooling techniques, thermoelectric cooling can offer numerous advantages. These include accurate temperature control and faster response, the opportunity for fanless operation (subject to heat sink performance), reduced noise, space savings, reduced power consumption and the ability to cool components to sub-ambient temperatures.
To read details, see https://www.digikey.com/en/articles/techzone/2018/feb/choosing-using-advanced-peltier-modules-thermoelectric-cooling